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Search Results for " tyrosine-protein kinase met "

Targets Recommended: c-Met/HGFR

2

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T7900	BAY-474	c-Met/HGFR	Tyrosine Kinase/Adaptors
	BAY-474 是酪氨酸蛋白激酶 c-MET 抑制剂，能够用于表观遗传学探针。
T14282	Amuvatinib hydrochloride HPK 56 hydrochloride,MP470 hydrochloride	Others	Others
	Amuvatinib hydrochloride (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret and is also a DNA repair suppressor through suppression of DNA repai

化合物

Cat.No: T7900

Target: c-Met/HGFR

Amuvatinib hydrochloride

Cat.No: T14282

Synonym: HPK 56 hydrochloride,MP470 hydrochloride

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00415	HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated SF receptor,HGF receptor,Scatter factor receptor,Tyrosin...	Human	HEK293 Cells
	Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which undergoes cotranslational proteolytic cleavage. Mature HGF R is a disulfide-linked dimer composed of a 50 kDa extracellular α chain and a 145 kDa transmembrane β chain. Proteolysis and alternate splicing generate additional forms of human HGF R which either lack of the kinase domai...
TMPY-02028	RON/CD136 Protein, Human, Recombinant (His) CD136,macrophage stimulating 1 receptor,CDw136,PTK8,RON	Human	HEK293 Cells
	The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. As the tyrosine kinase receptor is comprised of an extracellular domain, MST1R protein contains the ligand-binding pocket and an intracellular region where the kinase domain is located. MST1R signaling may be involved in the regulation of macrophage and T-lymphocyte activation in...
TMPJ-00375	HGF Protein, Human, Recombinant (His) Scatter factor,Hepatocyte growth factor,HGF,SF,Hepatopoietin...	Human	HEK293 Cells
	HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelia...
TMPK-00499	HGFR/c-Met Protein, Cynomolgus, Recombinant (His) MET,oncogene MET,cMET,SF receptor...	Cynomolgus	HEK293 Cells
	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. HGFR/c-Met ...
TMPK-00457	HGFR/c-Met Protein, Human, Recombinant (His & Avi) cMET,Met (c-Met),MET,HGF...	Human	HEK293 Cells
	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. HGFR/c-Met ...
TMPK-00634	MSPR/Ron Protein, Human, Recombinant (His) MST1R,RON,MSP R,CD136,PTK8,p185-Ron,MSPR,CDw136,MSP receptor	Human	HEK293 Cells
	Macrophage-stimulating protein (MSP) is a serum protein belonging to the plasminogen-related growth factor family. The specific receptor for MSP is the RON (recepteur d'origine nantais) receptor tyrosine kinase - a member of the MET proto-oncogene family. Activation of RON by MSP exerts dual functions on macrophages.
TMPH-03312	HGF Protein, Rat, Recombinant (GST)	Rat	E. coli
	Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. HGF Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 55.0 kDa and the accession number is P17945.

重组蛋白

HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated

Cat.No: TMPJ-00415

Species: Human

Expression System: HEK293 Cells

RON/CD136 Protein, Human, Recombinant (His)

Cat.No: TMPY-02028

Species: Human

Expression System: HEK293 Cells

HGF Protein, Human, Recombinant (His)

Cat.No: TMPJ-00375

Species: Human

Expression System: HEK293 Cells

HGFR/c-Met Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00499

Species: Cynomolgus

Expression System: HEK293 Cells

HGFR/c-Met Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00457

Species: Human

Expression System: HEK293 Cells

MSPR/Ron Protein, Human, Recombinant (His)

Cat.No: TMPK-00634

Species: Human

Expression System: HEK293 Cells

HGF Protein, Rat, Recombinant (GST)

Cat.No: TMPH-03312

Species: Rat

Expression System: E. coli

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